Super Avana (Avanafil with Dapoxetine)

Introduction

Super Avana is a medication specifically formulated to address two distinct but often related sexual health concerns in adult males: erectile dysfunction (ED) and premature ejaculation (PE). It combines two active ingredients, Avanafil and Dapoxetine, to offer a dual-action treatment. Avanafil, a phosphodiesterase type 5 (PDE5) inhibitor, works by increasing blood flow to the penis, facilitating an erection. Dapoxetine, a selective serotonin reuptake inhibitor (SSRI), acts by delaying ejaculation. Super Avana is available as a pill in a 100/60mg dosage strength.

Quick Reference Facts

Active Ingredient

Avanafil with Dapoxetine

Form

Pill (100/60mg)

Primary and Off-Label Uses

Erectile Dysfunction, Premature Ejaculation

What is Super Avana®?

Super Avana is a prescription medication designed to manage erectile dysfunction (ED) and premature ejaculation (PE) in adult men. It is a combination drug containing Avanafil, a PDE5 inhibitor, and Dapoxetine, an SSRI. As a generic medication, Super Avana offers a cost-effective alternative to branded treatments that contain the same active compounds. It is manufactured by various pharmaceutical companies globally, seeking to provide accessible solutions for men experiencing these common sexual health conditions. The combined action of its components offers a comprehensive approach to sexual function.

How Super Avana® Works

Super Avana works through the combined pharmacological actions of its two active ingredients: Avanafil and Dapoxetine.

Avanafil functions as a selective inhibitor of phosphodiesterase type 5 (PDE5). When a man is sexually stimulated, nitric oxide (NO) is released in the penile tissue. NO activates an enzyme called guanylate cyclase, which increases levels of cyclic guanosine monophosphate (cGMP). cGMP causes the smooth muscles in the penis to relax, increasing blood flow and leading to an erection. PDE5 is an enzyme that breaks down cGMP. By inhibiting PDE5, Avanafil prevents the breakdown of cGMP, prolonging its action and thus helping to achieve and maintain an erection during sexual activity. Avanafil is known for its relatively rapid onset of action compared to some other PDE5 inhibitors.

Dapoxetine, on the other hand, is specifically designed to treat premature ejaculation. It works by increasing the levels of serotonin in the brain. Serotonin is a neurotransmitter that plays a crucial role in mood, sleep, and sexual function. By selectively inhibiting the reuptake of serotonin, Dapoxetine enhances serotonergic neurotransmission. This modulation of serotonin pathways is believed to increase the latency of ejaculation and improve ejaculatory control. Dapoxetine has a short half-life, meaning it is quickly absorbed and eliminated by the body, which is desirable for an on-demand treatment for PE.

The synergistic effect of Avanafil and Dapoxetine in Super Avana allows it to simultaneously address the physiological basis of erectile dysfunction and the neurochemical pathways involved in premature ejaculation, providing a dual benefit for men experiencing both conditions.

Conditions Treated with Super Avana®

Super Avana is indicated for the treatment of erectile dysfunction (ED) and premature ejaculation (PE) in adult men.

• Erectile Dysfunction (ED): This condition is characterized by the consistent inability to achieve or maintain a penile erection sufficient for satisfactory sexual performance. Avanafil, one of the active ingredients in Super Avana, addresses this by enhancing the physiological response to sexual stimulation. It increases blood flow to the penis, facilitating engorgement and rigidity necessary for intercourse.
• Premature Ejaculation (PE): PE is defined as ejaculation that occurs sooner than desired, often within one minute of penetration, causing distress to the individual and his partner. Dapoxetine, the other component of Super Avana, serves to delay ejaculation. It works by modulating serotonin levels in the brain, which is believed to increase ejaculatory latency and improve control over the ejaculatory reflex.

By combining treatments for both ED and PE, Super Avana offers a comprehensive solution for men who experience co-occurring sexual dysfunctions.

Is Super Avana® the Right Medication for You?

Super Avana may be a suitable treatment option for adult men who are experiencing difficulties achieving or maintaining an erection (ED) and simultaneously struggle with ejaculating too quickly (PE). It is formulated for individuals who seek a consolidated approach to managing these distinct sexual health concerns. Its dual-action mechanism can be particularly beneficial for men whose sexual satisfaction is impacted by both issues.

Contraindications for Super Avana include known hypersensitivity to Avanafil, Dapoxetine, or any of their excipients. It should not be used by individuals taking nitrate medications (commonly prescribed for chest pain or angina) due to the significant risk of a dangerous drop in blood pressure. Similarly, it is not recommended for individuals with certain cardiovascular conditions, severe liver impairment, or those with a history of fainting associated with sexual activity. Caution is advised and medical consultation is essential for individuals with conditions such as low blood pressure, heart rhythm disorders, or a history of priapism. A healthcare professional can best assess individual health status, potential risks, and the suitability of Super Avana based on a patient's medical history and other medications.

Buying Super Avana® from Our Online Pharmacy

Why Choose Our Service?

For men seeking effective treatment for both erectile dysfunction and premature ejaculation, our online pharmacy provides a convenient and discreet pathway to access Super Avana. We understand that managing sexual health concerns can be sensitive, and our service is designed to offer a straightforward solution without the potential embarrassment or inconvenience of high-street pharmacies. We aim to make obtaining essential medications like Super Avana accessible and manageable for our customers.

Quality & Safety Assurance

We facilitate access to medications through verified international partners operating under recognized regulatory frameworks. These partners adhere to stringent quality control measures, ensuring that the Super Avana we provide is manufactured to high standards of purity, potency, and consistency. Our supply chain is carefully managed to maintain product integrity from sourcing to delivery.

Pricing & Access

Super Avana, being a generic alternative, offers significant cost savings compared to branded medications that contain Avanafil and Dapoxetine separately or in combination. Our pharmacy service strives to offer competitive pricing, making effective treatment more affordable and accessible. We provide access to this medication for individuals who may otherwise find it difficult to obtain through their local healthcare providers or are looking to manage their healthcare expenses more effectively.

Discreet Delivery

Your privacy is paramount. We ensure that all orders, including Super Avana, are packaged discreetly with no outward indication of the contents. This allows you to receive your medication with complete peace of mind. We offer reliable delivery options with express delivery typically within 7 days or standard airmail in approximately 3 weeks, ensuring you receive your treatment promptly and privately.

Use: Dosing, Missed Dose, Overdose

Dosing Information

Super Avana is typically taken as a single unit-dose pill containing 100mg of Avanafil and 60mg of Dapoxetine. It is generally recommended to take one pill approximately 1 to 3 hours before sexual activity. The maximum recommended dose is one pill daily. It is important not to exceed the prescribed dosage or frequency. The medication should not be taken with meals high in fat, as this can reduce its absorption and efficacy.

Missed Dose

If you miss taking Super Avana for a planned sexual encounter, take it as soon as you remember, provided it is within the recommended timeframe before anticipated sexual activity. If it is too close to the time you plan to engage in sexual activity, or if you have already engaged in sexual activity, skip the missed dose. Do not take a double dose to make up for a missed one, as this could increase the risk of side effects. Always follow your healthcare provider's advice regarding missed doses.

Overdose

In the event of an overdose of Super Avana, symptoms may be more pronounced versions of the common side effects associated with Avanafil and Dapoxetine. These could potentially include severe dizziness, fainting, prolonged and painful erections (priapism), nausea, vomiting, or significant changes in heart rate or blood pressure. If an overdose is suspected, seek immediate medical attention. It is advisable to bring any remaining medication packaging or the pills themselves to help medical professionals identify the issue quickly.

Practical Precautions

• Alcohol Consumption: Excessive alcohol intake can increase the risk of side effects such as dizziness, drowsiness, and a drop in blood pressure. It may also impair erectile function. It is advisable to limit alcohol consumption when taking Super Avana.
• Operating Machinery: Due to potential side effects like dizziness and visual disturbances, caution should be exercised when driving or operating heavy machinery after taking Super Avana.
• Timing with Food: Avoid taking Super Avana with high-fat meals, as this can significantly affect the absorption and effectiveness of both Avanafil and Dapoxetine.

Safety Information

⚠️ Who Should Not Take Super Avana®

• Nitrate Use: Individuals taking any form of nitrate medication (e.g., glyceryl trinitrate, isosorbide mononitrate/dinitrate) should absolutely not take Super Avana. Co-administration can lead to a severe and potentially life-threatening drop in blood pressure.
• MAO Inhibitors: Patients currently receiving treatment with monoamine oxidase inhibitors (MAOIs) or who have taken them within the last 14 days should not use Super Avana. Similarly, individuals taking linezolid or methylene blue should consult their doctor.
• Hypersensitivity: Those with a known allergy or hypersensitivity to Avanafil, Dapoxetine, or any other component of Super Avana should avoid taking this medication.
• Severe Cardiac or Liver Conditions: Super Avana is not recommended for individuals with severe heart conditions (e.g., recent heart attack, stroke, heart failure) or severe hepatic impairment.
• History of Fainting: Individuals with a history of fainting (syncope), particularly if related to sexual activity, should exercise extreme caution or avoid Super Avana.
• Certain Other Medications: Use with caution or avoid in conjunction with other medications that affect blood pressure or serotonin levels. A thorough review of all concomitant medications with a healthcare professional is essential.

Common Side Effects

The following side effects are generally mild to moderate and often temporary for Super Avana:

• Headache
• Dizziness
• Nausea
• Flushing (redness or warmth in the face or chest)
• Nasal congestion
• Indigestion (dyspepsia)
• Insomnia (difficulty sleeping)
• Fatigue
• Diarrhoea
• Increased sweating

These side effects typically resolve on their own as your body adjusts to the medication. If they are persistent or bothersome, consult your healthcare provider.

Serious Side Effects (Seek Immediate Medical Help)

While rare, serious side effects can occur. Seek immediate medical attention if you experience any of the following:

• Priapism: An erection that lasts for more than 4 hours and is painful. This is a medical emergency that requires prompt treatment to prevent permanent damage.
• Sudden Vision Changes: Including blurred vision, changes in colour perception, or loss of vision in one or both eyes. This could be a sign of a serious eye condition like non-arteritic anterior ischemic optic neuropathy (NAION).
• Sudden Hearing Changes: Including ringing in the ears (tinnitus) or sudden loss of hearing.
• Severe Allergic Reactions: Symptoms may include rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, or difficulty breathing.
• Seizures: Uncontrolled electrical activity in the brain.
• Significant Drop in Blood Pressure: Symptoms can include severe dizziness, light-headedness, or fainting, especially upon standing.

Drug & Food Interactions

Super Avana can interact with various substances, potentially altering its effectiveness or increasing the risk of side effects:

• Nitrates: As mentioned, combining with nitrates (used for chest pain) is strictly contraindicated and can cause severe hypotension.
• Alpha-Blockers: Medications used for prostate and blood pressure issues (e.g., terazosin, doxazosin) can cause symptomatic low blood pressure, especially orthostatic hypotension, when taken with PDE5 inhibitors. Taking them together is generally not recommended unless carefully monitored.
• Other PDE5 Inhibitors: Do not combine Super Avana with other medications for erectile dysfunction (e.g., sildenafil, tadalafil, vardenafil).
• CYP3A4 Inhibitors/Inducers: Certain medications acting on the liver enzyme CYP3A4 can affect Avanafil and Dapoxetine levels. Strong CYP3A4 inhibitors (e.g., ketoconazole, ritonavir) may increase concentrations of Avanafil and Dapoxetine. Moderate inhibitors (e.g., erythromycin, diltiazem) require caution. Potent inducers (e.g., rifampicin) may decrease their effectiveness.
• Serotonergic Drugs: Combining Dapoxetine with other serotonergic agents, such as SSRIs, SNRIs, triptans, lithium, St. John's Wort, or certain pain medications (tramadol), can increase the risk of serotonin syndrome, a potentially life-threatening condition.
• Alcohol: As noted in the Dosing section, alcohol can increase the risk of dizziness and hypotension and may impair erectile function.
• Grapefruit Juice: High consumption of grapefruit juice can inhibit CYP3A4, potentially increasing the plasma concentrations of Avanafil and Dapoxetine, leading to increased side effects. It is advisable to limit intake.

Off-Label and Investigational Uses of Super Avana®

While Super Avana is formally approved for the combined treatment of erectile dysfunction and premature ejaculation, some investigational uses or scenarios may arise in clinical practice. Specific investigational uses are not highlighted in publicly available data; however, given the components, individual components might be studied or used in ways not explicitly covered by standard indications.

For instance, Avanafil alone is sometimes explored for conditions where improved penile blood flow is beneficial, though such uses are not generally within the scope of a combined medication like Super Avana. Similarly, Dapoxetine's role in modulating sexual response could theoretically be explored in other contexts beyond PE, but its use in Super Avana is targeted at the dual ED/PE indication.

It is crucial to reiterate that any use of Super Avana outside its approved indications should strictly occur under the direct supervision of a qualified healthcare provider. The efficacy and safety profile for such non-approved uses have not been established by regulatory authorities, and potential risks may not be fully understood.

Storage & Handling

Super Avana pills should be stored at room temperature, typically between 15°C to 30°C (59°F to 86°F). Protect the medication from excessive heat, light, and moisture. Do not store it in the bathroom, as the humidity and temperature fluctuations in that environment can degrade the medication. Keep Super Avana and all medications securely stored out of the reach and sight of children and pets. Always check the expiry date on the packaging. Do not use medication that has passed its expiry date. Unused or expired medication should be disposed of safely. Consult your local pharmacy or waste disposal guidelines for information on how to properly discard medications to prevent environmental contamination.

Frequently Asked Questions

About Using Super Avana®

• Can I take Super Avana while on holiday in a very hot climate? High temperatures can potentially affect medication stability. It's best to store Super Avana in a cool, dry place, away from direct sunlight, even when travelling. If your accommodation lacks air conditioning, seek a stable, cooler spot.

• Does Super Avana need to be taken with food? It is generally advised to take Super Avana on an empty stomach or after a light meal. High-fat meals can reduce the absorption and effectiveness of both Avanafil and Dapoxetine, delaying the onset of action.

• How does Super Avana interact with supplements like vitamins or herbal remedies? The interaction potential with supplements is less documented than with prescription drugs. However, some herbal products can have potent effects. It is always prudent to inform your doctor or pharmacist about all supplements you are taking to ensure no unknown interactions occur.

Product Information

• What is the appearance of a Super Avana pill? Super Avana pills are typically oval-shaped and film-coated. Each pill contains 100mg of Avanafil and 60mg of Dapoxetine. The specific colour and markings can vary by manufacturer.

• Are there inactive ingredients in Super Avana that I should be aware of? Yes, like most medications, Super Avana contains inactive ingredients (excipients) such as microcrystalline cellulose, hydroxypropyl cellulose, croscarmellose sodium, magnesium stearate, and film-coating. These are generally considered safe and do not contribute to the medicinal effects but can be relevant for individuals with specific allergies.

Safety & Regulations

• Will taking Super Avana affect my ability to drive or operate machinery? Super Avana can cause dizziness and visual disturbances. It is advisable to avoid driving or operating heavy machinery if you experience these side effects until they subside and you are confident in your ability to perform these tasks safely.

• Can I take Super Avana if I have a history of low blood pressure? Individuals with a history of hypotension should use Super Avana with caution. Both ingredients can potentially affect blood pressure. It’s crucial to discuss your medical history with your doctor to determine if this medication is appropriate for you.

• Does Super Avana have any implications for sports or athletic performance testing? While Super Avana is not a performance-enhancing drug, its active ingredients could potentially be flagged in certain drug tests depending on the specific testing panel and substances monitored. Athletes should consult their sport's governing body or medical advisor.

Glossary

Phosphodiesterase Type 5 (PDE5) Inhibitor

A class of drugs that work by blocking the action of the PDE5 enzyme, thereby increasing blood flow to the penis to treat erectile dysfunction.

Selective Serotonin Reuptake Inhibitor (SSRI)

A type of antidepressant medication that works by increasing levels of serotonin in the brain, often used to treat conditions like depression, anxiety, and premature ejaculation.

Serotonin Syndrome

A potentially life-threatening condition caused by too much serotonin activity in the body, often a result of combining serotonergic medications.

Hypotension

Low blood pressure, which can cause dizziness, lightheadedness, and fainting.

Priapism

A prolonged and painful erection of the penis lasting more than four hours, requiring immediate medical attention.

Disclaimer

The information presented about Super Avana is intended for general informational purposes only and is not a substitute for professional medical advice. All treatment decisions, including the use of medications for off-label purposes, must be made under the direct supervision of a qualified healthcare provider. We assume that all individuals accessing this information are responsible adults capable of making informed health choices. Our online pharmacy service provides access to medications such as Super Avana for individuals who may face challenges with local availability, cost, or prescription-based access, offering a legitimate alternative for obtaining necessary treatments. It is essential to consult your doctor before initiating, altering, or discontinuing any medication regimen.