Generic Priligy (Dapoxetine)

Introduction

Priligy is a medication designed to help adult men manage a specific sexual concern: premature ejaculation (PE). Available as a pill, it contains the active ingredient Dapoxetine. Typically offered in 30mg, 60mg, and 90mg strengths, Priligy belongs to a class of drugs known as selective serotonin reuptake inhibitors (SSRIs). While primarily developed and approved for PE, its pharmacological action means it primarily addresses the neurochemical pathways involved in ejaculatory reflex control.

Quick Reference Facts

Active Ingredient

Dapoxetine

Form

Pill (dosages = 30mg, 60mg, 90mg)

Primary and Off-Label Uses

Premature Ejaculation (PE)

What is Priligy?

Priligy is a prescription medication formulated as a pill, containing the active compound Dapoxetine. It is classified as a short-acting selective serotonin reuptake inhibitor (SSRI) specifically designed for the treatment of premature ejaculation (PE) in adult males. Priligy is a brand-name medication, but generic versions containing Dapoxetine are also available, which may offer a more cost-effective alternative. The development of Dapoxetine focused on its rapid absorption and elimination, distinguishing it from longer-acting SSRIs often used for depression.

How Priligy Works

Priligy works by increasing the levels of a neurotransmitter in the brain called serotonin. Serotonin plays a crucial role in regulating mood, but it also influences nerve signalling pathways that control ejaculation. Dapoxetine, the active ingredient in Priligy, selectively inhibits the reuptake of serotonin, thereby increasing its concentration in the synaptic cleft (the space between nerve cells). This enhanced serotonergic activity is believed to delay the ejaculatory reflex by acting on specific receptors and neural pathways within the central nervous system, primarily in the brain and spinal cord.

The rapid absorption of Dapoxetine, with peak plasma concentrations typically reached within 1-2 hours after administration, allows it to be taken on an as-needed basis before anticipated sexual activity. Its relatively short half-life means that it is usually eliminated from the body within approximately 24 hours, which helps to minimise the risk of accumulation and associated prolonged side effects seen with some other SSRIs. This pharmacokinetic profile is key to its suitability for treating PE, where immediate-acting efficacy is desired.

Conditions Treated with Priligy

Priligy is approved in many countries for the treatment of premature ejaculation (PE) in adult men aged 18 to 64 years.

• Premature Ejaculation (PE): Priligy is indicated for men who experience persistently ejaculation occurring, on average, within two minutes of penetrative. This must be accompanied by considerable personal distress or interpersonal difficulty. PE is often characterised by a lack of perceived ejaculatory control. Priligy helps to increase the time taken to ejaculate by modulating the serotonergic pathways involved in the ejaculatory reflex, thereby enhancing control and reducing distress associated with the condition.

Is Priligy the Right Medication for You?

Priligy is considered for adult men who actively experience premature ejaculation and find it causes significant distress or interpersonal difficulties. If you consistently ejaculate very quickly after penetration, typically within two minutes, and this causes you or your partner concern, Priligy may be an option to discuss with a healthcare professional. It is intended for situational use, meaning it is taken before sexual activity rather than daily.

Priligy is generally not appropriate for individuals who do not experience PE. It is also not recommended for men with certain pre-existing medical conditions, such as moderate to severe liver impairment, or those taking specific medications, particularly monoamine oxidase inhibitors (MAOIs) or other SSRIs/SNRIs, due to the risk of serious interactions. Patients with a history of fainting, dizziness, or certain heart conditions should also exercise caution. A thorough medical evaluation is essential to determine suitability.

Buying Priligy from Our Online Pharmacy

Why Choose Our Service?

For men seeking an effective solution for premature ejaculation, accessing Priligy should be straightforward and discreet. Our online pharmacy provides a convenient and reliable way to obtain Priligy and its generic equivalent, Dapoxetine, ensuring you can manage your condition with confidence and privacy. We aim to simplify access to essential medications, helping you regain control and improve your sexual well-being without unnecessary complications.

Quality & Safety Assurance

We are committed to providing high-quality medications. We facilitate access to Priligy and generic Dapoxetine through verified international partners operating under recognised regulatory frameworks. These partners adhere to stringent quality standards, ensuring that every pill you receive is authentic, safe, and effective, mirroring the standards expected from reputable pharmacies.

Pricing & Access

Our service strives to offer competitive pricing for Priligy and its generic alternative, Dapoxetine. By optimising our supply chain and sourcing intelligently, we can provide these medications at a more affordable cost compared to traditional high-street chemists, especially when considering the generic versions of Dapoxetine. This accessibility helps more men manage PE effectively without financial burden.

Discreet Delivery

Understanding the sensitive nature of sexual health concerns, our service prioritises your privacy. All orders are processed and dispatched with the utmost discretion. Medications are packaged in plain, unmarked boxes, ensuring complete confidentiality. We offer reliable delivery options; with express delivery typically within 7 days or standard airmail in approximately 3 weeks, your medication arrives safely and discreetly at your doorstep.

Use: Dosing, Missed Dose, Overdose

Dosing:

• Priligy (Dapoxetine) is typically initiated at a dose of 30mg, taken approximately 1-3 hours before anticipated sexual activity.
• If the initial dose is insufficient and well-tolerated, the dosage may be increased to 60mg. The maximum recommended dose is 60mg within a 24-hour period.
• It is important not to exceed the recommended dosage. Priligy should not be taken more than once in a 24-hour period.

Missed Dose:

• If you miss a dose of Priligy, take it only if you anticipate sexual activity in the next 1-3 hours.
• Do not take a missed dose if sexual activity does not occur as planned or if it is close to your next scheduled sexual activity.
• Never double the dose to make up for a missed one.

Overdose:

• Symptoms of Priligy overdose are not well-documented, but if a significant overdose is suspected, seek immediate medical attention.
• Symptoms might theoretically include increased intensity of common side effects such as nausea, vomiting, dizziness, or drowsiness.
• Contact your local emergency services or a poison control centre for guidance.

Practical Precautions:

• Alcohol: Avoid consuming alcohol while taking Priligy, as it can increase the risk of side effects such as dizziness, drowsiness, impaired judgment, and fainting.
• Operating Machinery: Priligy can cause dizziness, impaired concentration, and other central nervous system effects. Avoid driving or operating heavy machinery until you know how Priligy affects you.
• Administration: Priligy pills should be swallowed whole with a full glass of water. They can be taken with or without food.

Safety Information

⚠️ Who Should Not Take Priligy

Priligy is contraindicated in individuals with:

• Hypersensitivity: Known allergy or hypersensitivity to Dapoxetine or any of the inactive ingredients.
• Certain Medical Conditions: Moderate to severe hepatic impairment.
• Concomitant Medications: Use of monoamine oxidase inhibitors (MAOIs) or within 14 days of stopping an MAOI. Similarly, do not use within 7 days of stopping other SSRIs, SNRIs, tricyclic antidepressants, or opioid antagonists like tramadol. Use with thioridazine is also contraindicated.
• History of Syncope: Such as vasovagal syncope.
• Severe Cardiovascular Conditions: Including uncontrolled hypertension, uncompensated heart failure, or significant valvular or conduction disease.
• History of Mania or Severe Depression: Patients with a history of bipolar disorder or severe depressive episodes.

Common Side Effects

The most frequently reported side effects of Priligy include:

• Nausea
• Dizziness
• Headache
• Diarrhoea
• Fatigue
• Insomnia (difficulty sleeping)
• Erectile dysfunction
• Decreased libido
• Anxiety or agitation
• Dry mouth

These side effects are generally mild to moderate and often resolve with continued use or adjustment of dosage. If they are persistent or bothersome, consult your healthcare provider.

Serious Side Effects (Seek Immediate Medical Help)

Although rare, serious side effects can occur. Seek immediate medical attention if you experience any of the following:

• Fainting (Syncope): Especially if accompanied by dizziness or lightheadedness. This risk is increased when alcohol is consumed.
• Suicidal Thoughts or Behaviour: As with many SSRIs, there is a theoretical risk of increased suicidal ideation, particularly upon initiation of treatment or dose change. Any sudden changes in mood, behaviour, or thoughts of self-harm require urgent medical evaluation.
• Serotonin Syndrome: A potentially life-threatening condition characterised by symptoms such as agitation, hallucinations, rapid heartbeat, fever, muscle stiffness, loss of coordination, nausea, vomiting, or diarrhoea.
• Allergic Reactions: Including rash, itching, swelling (especially of the face, tongue, or throat), severe dizziness, or trouble breathing.

Drug & Food Interactions

• MAOIs and Other Antidepressants/Opioids: Combining Priligy with MAOIs, other SSRIs, SNRIs, tricyclic antidepressants, or opioid antagonists can lead to serious interactions, including serotonin syndrome.
• Thioridazine: This antipsychotic medication should not be used with Priligy.
• CNS Depressants: Caution is advised when Priligy is taken with alcohol or other central nervous system depressants (e.g., sedatives, hypnotics), as this combination can increase the risk of fainting and other central nervous system side effects.
• Drugs Affecting Cytochrome P450 Enzymes: While Dapoxetine is metabolised by CYP2D6, CYP1A2, and CYP2C19, moderate inhibitors of CYP2D6 (such as certain antidepressants, antipsychotics, and antiarrhythmics) may increase Dapoxetine exposure.
• Grapefruit Juice: While not a contraindication, consuming large amounts of grapefruit juice may potentially affect how Priligy is processed by the body. It is advisable to discuss dietary habits with your healthcare provider.

Off-Label and Investigational Uses of Priligy

While Priligy (Dapoxetine) is specifically approved for the treatment of premature ejaculation (PE), research and clinical observations have explored its potential in other areas, though these uses are considered off-label and have not received formal regulatory approval for such indications.

• Symptomatic Treatment of Obsessive-Compulsive Disorder (OCD): Some studies have investigated Dapoxetine as an adjunctive therapy for OCD, hypothesising that its SSRI properties could help manage repetitive thoughts and behaviours. However, evidence for its efficacy in this context is limited and not considered a primary treatment.
• Premature Ejaculation in Specific Patient Groups: Although approved for adult men, its use in certain populations or for particular types of PE has been a subject of clinical interest. For instance, its rapid onset of action might be considered in specific clinical scenarios where flexibility is paramount.

It is crucial to reiterate that any use of Priligy outside its approved indication for PE should only be undertaken under the strict supervision of a qualified healthcare provider who can assess the potential benefits against the known risks, as specific safety and efficacy data for these off-label uses may be limited or inconclusive.

Storage & Handling

Priligy should be stored at room temperature, typically between 15°C and 30°C (59°F and 86°F). Keep it away from excessive heat, cold, and direct light. The medication should be stored in its original packaging to protect it from moisture. Avoid storing it in damp environments like bathrooms. Ensure that Priligy is kept out of reach of children and pets. If the medication has expired, do not use it. Dispose of expired or unused Priligy according to local guidelines for pharmaceutical waste disposal; do not flush it down the toilet unless specifically instructed to do so.

Frequently Asked Questions

About Using Priligy

• Can I take Priligy with grapefruit juice? While Priligy is not strictly contraindicated with grapefruit juice, consuming large quantities might affect how your body processes the medication, potentially increasing the concentration of Dapoxetine in your system. It is advisable to limit intake or discuss this with your healthcare provider.

• Is it safe to take Priligy while traveling across time zones? Yes, Priligy can be taken across time zones, but it is important to maintain the intended timing relative to sexual activity. Take the tablet approximately 1 to 3 hours before you anticipate sexual intercourse, regardless of the local time.

• How does Priligy interact with other medications for erectile dysfunction (ED)? Priligy may be taken by men with PE who also have erectile dysfunction, provided they are not taking particular medications like alpha-blockers. However, combining these medications without medical guidance can increase the risk of adverse effects such as dizziness and fainting. Always consult your doctor.

Product Information

• What do Priligy tablets look like? Priligy tablets are typically described as either round or oval and may be film-coated. The colour can vary depending on the dosage strength. For example, 30mg tablets are often blue-green, 60mg are a darker blue-green, and 90mg might be a different shade or size. Always refer to the specific packaging.

• Can I split or crush Priligy tablets? No, Priligy tablets are not designed to be split, crushed, or chewed. They should be swallowed whole with a glass of water to ensure proper absorption and efficacy, and to avoid potential irritation or altered pharmacokinetics.

Safety & Regulations

• Will Priligy show up on a drug test? Priligy is not typically screened for on standard drug tests for illicit substances. However, it is an SSRI, and if a specific test for antidepressant medications were conducted, it could potentially be detected. It is not a substance of abuse.

• Are there any specific warnings for elderly men taking Priligy? While the approved age range for Priligy is typically 18-64 years, caution is advised in older individuals due to potentially increased susceptibility to side effects like dizziness and fainting. A healthcare provider will assess individual risk factors before prescribing.

• What is the difference between Priligy and generic Dapoxetine? Priligy is the brand-name medication. Generic Dapoxetine contains the same active ingredient, works in the same way, and is considered bioequivalent. Generic versions are often available at a lower cost than the brand-name product.

• Can Priligy be used by individuals sensitive to SSRIs? Individuals with a known hypersensitivity or adverse reaction to other SSRIs should exercise extreme caution and consult their healthcare provider. While Dapoxetine has a different pharmacokinetic profile, there can be cross-reactivity in terms of side effects.

Glossary

Selective Serotonin Reuptake Inhibitor (SSRI)

A class of antidepressant medications that work by increasing the levels of serotonin in the brain.

Neurotransmitter

A chemical messenger that transmits signals between nerve cells (neurons) in the brain and nervous system.

Synaptic Cleft

The small gap between two neurons where nerve impulses are transmitted from one neuron to another.

Pharmacokinetics

The study of how drugs are absorbed, distributed, metabolised, and excreted by the body.

Ejaculatory Reflex

The physiological process that leads to ejaculation, controlled by the central and peripheral nervous systems.

Disclaimer

The information provided about Priligy is intended for general knowledge and informational purposes only. It does not constitute professional medical advice, diagnosis, or treatment. All treatment decisions, including those concerning the use of Priligy for approved indications, off-label applications, or any adjustments to existing therapy, must be made under the direct supervision of a qualified healthcare provider. Readers are advised that self-medication is dangerous, and seeking professional medical consultation is essential before starting, changing, or discontinuing any medication. We assume all individuals accessing this information are responsible adults capable of making informed health decisions. Our online pharmacy service is designed to provide convenient access to Priligy and generic Dapoxetine for those who may have limited access through traditional channels or seek cost-effective options. However, it is imperative to consult with your doctor to determine if Priligy is appropriate for your specific health needs.